Cannabis is commonly used among reproductive-aged individuals, and prenatal cannabis use (PCU) has increased dramatically in recent years, despite guidance w…
Probiotics and palmitoylethanolamide (PEA) for osteoarthritic pain: individual effects in a multiple baseline design study.
Osteoarthritis (OA) is a leading cause of chronic pain. As healthcare services struggle to meet demand to treat chronic pain, many individuals self-manage th…
The Effects of an Acute Dose of Cannabidiol on Health and Two-Mile Time Trial Performance-A Pilot Study.
CED Clinical Relevance #64Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. 🔬 Evidence Watch | CED Clinic CbdExerciseAthletic PerformancePilot StudyCardiovascular JournalNutrientsStudy TypePilot StudyPopulationHuman participants Why This MattersThis pilot study addresses a growing clinical...
Small Pilot Trial Finds Medicinal Cannabis Feasible to Study in Adolescents with Tourette Syndrome — But Efficacy Remains Unknown
The findings suggest that the study protocol is feasible and acceptable to patients with TS and their families. A fully powered study is needed to evaluate the efficacy of MC in adolescent TS.
Pilot Study Finds Salivary Metabolite Shifts in Autistic Children Treated with Medical Cannabis—But Evidence Remains Preliminary
“Sixty-five potential cannabis-responsive biomarkers exhibiting a shift toward the TD physiological levels were identified in children with ASD after MC treatment.” — Authors’ caution that larger trials are needed is appropriate, but the term ‘Cannabis-Responsive’ implies causation the design cannot support.
Regular Cannabis Use is Associated with a Diminished Anandamide Response to a Standard Exercise Stimulus: A Pilot Study.
The endocannabinoid system (ECS) is increasingly recognized as an important regulator of many physiological systems. People who use products derived from Twe…
Phase 1 Open-Label Pilot Trial of H4 Deep Repetitive Transcranial Magnetic Stimulation for Adults With Moderate-to-Severe Cannabis Use Disorder.
Cannabis use disorder (CUD) is a significant public health problem and no medical treatments have received regulatory approval to date. Deep repetitive trans…
Exploring the neuroprotective effects of phytocannabinoids on oxygen-glucose deprived neurons in an in vitro model of stroke.
Stroke is a leading cause of death and disability worldwide, but therapeutic options to reduce or prevent neuronal damage are extremely limited. Cannabinoids…
Pilot study on cannabis-induced alterations in platelet function: implications for transfusion medicine.
Platelet transfusions are essential in the management of thrombocytopenia, bleeding disorders, and hematologic malignancies. With cannabis use rising worldwi…
Cannabidiol & Glucose Tolerance: Clinical Evidence Review
Clinical Takeaway In this pilot study, short-term low-dose CBD supplementation did not measurably improve glucose tolerance or beneficially alter the gut microbiome in sedentary adults with overweight or obesity. While animal research...