Cannabidiol in Developmental Epilepsy: Organoid-Guided Precision Medicine Across Critical Neurodevelopmental Windows.
CBD neurodevelopmental epilepsy research reveals promising precision medicine approaches targeting critical developmental windows. This review synthesizes evidence on CBD's neuroprotective and antiseizure effects in pediatric epilepsy. Understanding…
Phase 2 Open-Label INSPIRE Trial on Transdermal CBD Gel in 22q11.2 Deletion Syndrome
The INSPIRE trial investigates transdermal cannabidiol gel children with 22q11.2 deletion syndrome to assess safety and tolerability. This phase 2 open-label study provides preliminary data on CBD gel use in pediatric neurodevelopmental disorders.…
Colorado: Data Finds No Evidence of Underage Cannabis Sales at Licensed Retailers
Colorado cannabis regulatory compliance data shows no evidence of underage cannabis sales at licensed retailers. This supports the effectiveness of state oversight in preventing direct retail access to minors. Clinicians should focus on secondary access…
Drugs Detected in Suspected Pediatric Exposures: A 5-Year Review
This 5-year review focuses on pediatric cannabis exposure detection in suspected toxic ingestions. Comprehensive toxicology testing reveals cannabis metabolites as common findings. The study emphasizes the need for thorough screening in pediatric…
Parent and Caregiver Perceptions of Cannabidiol Products May Put Children at Risk
Pediatric cannabidiol exposure risks are rising alongside the growth of the CBD market. Understanding caregiver perceptions is critical to preventing unintentional exposure. This study highlights the need for improved safety education and childproof…
Cannabidiol Blood Metabolite Levels and EEG Changes in Autism
This study on autism spectrum disorder cannabidiol research reveals that CBD blood metabolite levels are associated with EEG changes. Boys with autism showed improvements in visuomotor and non-verbal cognitive abilities after cannabidiol treatment. These…
Medical Cannabis and Epilepsy: Reviewing the Evidence
Cannabis epilepsy treatment evidence highlights the anticonvulsant properties of CBD and THC in managing seizures. Approximately 30% of epilepsy patients have drug-resistant forms that may benefit from cannabis-based therapies. Understanding this…
Medical Cannabis Use in Autism: Patient Characteristics and Guidelines
This study examines medical cannabis prescribing patterns autism in a large Israeli HMO. It highlights patient characteristics and alignment with national guidelines. Evidence for medical cannabis use in autism remains limited but growing.
Medicinal Cannabis Extract NTI164 Modulates Pediatric Neuropsychiatric Pathways
Pediatric cannabis neuropsychiatric research reveals NTI164, a low-THC cannabis extract, modifies epigenetic, ribosomal, and immune pathways in PANS. This study provides early molecular insights into cannabis effects on pediatric neuropsychiatric…
Therapeutic Use of Cannabis Derivatives for Autism: Systematic Review
The therapeutic cannabis autism systematic review evaluates randomized clinical trials on cannabis derivatives for autism spectrum disorder. Evidence suggests potential benefits but remains limited by low certainty and methodological variability. Larger,…
