Cannabis for orthopaedic pain is a growing topic, but this 2025 systematic review does not settle the question. It found mixed signals across small, heterogeneous trials, with more placebo-controlled wins than active-comparator wins. For clinicians and patients alike, cannabis for orthopaedic pain remains promising in spots, but far from standardized.
Medical Cannabis for Orthopaedic Pain: Promising Signal, Weak Evidence Base
The review reveals minimal high-quality evidence supporting the efficacy of medical cannabis in the targeted orthopaedic areas. Most evidence suggests effectiveness only when compared with no treatment or placebo, with limited data against active comparators.