Cannabinoids and the Aging Brain: Why Dose and Product Type Matter
A review in Frontiers in Pharmacology examined dose-effect complexities and challenges in cannabinoid therapy for aging-related neurobiological changes. Dr. Caplan reviews this cannabinoids aging brain dose research and why the same product can behave…
High-THC Cannabis and Inflammation: What the New Metabolic Trial Actually Found
A quasi-randomized trial published in Scientific Reports tested acute inflammatory and metabolic effects of inhaling high-THC cannabis. Dr. Caplan reviews this high THC cannabis inflammation trial, which found inflammatory markers rose after use while…
The Medication Weaning Roadmap: How to Safely Talk to Your Doctor About Deprescribing
A physician's guide to safely deprescribing psychiatric medications in autism, recognizing akathisia, and using cannabinoids as a calming bridge.
Sugar-Free THC Edibles for Diabetics: What the Sweetener Evidence Actually Shows
A physician reviews the evidence on cannabis-edible sweeteners, including a cardiovascular signal for erythritol that diabetic patients should know about.
CBD for Anxiety: What 12 Brain-Imaging Studies Actually Show
A 2026 systematic review pooled 12 human neuroimaging studies using fMRI, PET, and SPECT to test whether CBD produces a consistent brain-imaging signature for anxiety and stress. Dr. Caplan walks through why the amygdala findings splinter in both…
The Polypharmacy Cascade: When Medication Side Effects Are Misdiagnosed as New Illness
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Healthcare Governance in the Family Office: The Critical Role of an Independent Medical Quarterback
"Wealth management without healthcare governance leaves families vulnerable to the most consequential blind spot of all: assuming that world-class institutional access is the same as coordinated clinical judgment." Single and multi-family…
Cannabis Craving Linked to PTSD Symptoms in Trauma Survivors
Understanding the link between PTSD symptoms and cannabis craving is crucial for developing effective treatment strategies, especially in light of increasing medical marijuana usage.
Cannabis and Working Memory: Brain Imaging Study Explains Cognitive Impact
The 2026 cannabis working memory study highlights significant findings on cognitive effects. It shows how cannabis use correlates with reduced brain activity in working memory tasks. Understanding these implications is crucial for patient counseling and…
Cannabinoids and the Aging Brain: Why Dose and Product Type Matter
A 2026 review highlights how cannabinoid therapy aging brain effects depend on dose, product type, and aging physiology. The findings emphasize careful, age-adapted decisions over broad claims. This supports safer cannabis use tailored to older adults'…
