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Running CBD and the Ketogenic Diet Together: What a 58-Patient Johns Hopkins Cohort Found
A multicenter Johns Hopkins cohort of 58 patients is the first published account of using CBD and ketogenic diet for epilepsy at the same time, and ketosis held in 87 percent of them. Seizure outcomes resembled what either therapy produces alone, with…
Pre-Seizure Symptoms: What an Aura Is, What a Prodrome Is, and Why the Difference Matters Diagnostically
Pre-seizure symptoms fall into two categories that get confused constantly. The aura, which the 2017 International League Against Epilepsy classification treats as the beginning of a focal aware seizure, carries localizing value, while the prodrome can…
CBDV vs CBD: What All Six Registered Clinical Trials of
This cannabidivarin clinical trials review examines all six peer-reviewed studies to date, highlighting that adequately powered trials for epilepsy and neuropathic pain failed to show benefit. The review clarifies what the current evidence supports and…
CBD and Nonseizure Outcomes in Epilepsy: What a New Systematic Review Shows
This systematic review examines CBD nonseizure outcomes epilepsy, analyzing 32 studies with 1,343 patients. It reports consistent improvements in cognition, behavior, and other nonseizure domains, though evidence is mostly observational and requires…
Purified CBD and Epilepsy: Insights on Nonseizure Outcomes from New Review
A recent systematic review examined highly purified cannabidiol epilepsy treatment focusing on nonseizure outcomes such as cognition, behavior, and quality of life. The evidence, mainly observational, suggests potential benefits but remains inconclusive…
California Bill to Authorize Medical Cannabis Drive-Thrus Advances to Assembly Floor Vote
✦ New CED Clinical Relevance #45 Clinical Context Background information relevant to the evolving cannabis medicine landscape. PolicyIndustry Why This Matters This bill could expand patient access to medical cannabis by removing logistical…
Efficacy of pharmacological treatments for Dravet syndrome: Systematic review and network …
✦ New CED Clinical Relevance #85 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. ResearchNeurologyCBDPediatricsSafety Why This Matters This systematic review and network meta-analysis provides…
CBD improves neuropsychiatric symptoms in tuberous sclerosis complex: EpiCom trial insights
The EpiCom trial highlights CBD neuropsychiatric symptoms tuberous sclerosis benefits beyond seizure control. This study provides evidence that CBD may improve behavioral and cognitive symptoms in TSC patients. These findings suggest new therapeutic…
Fund a Medical Cannabis Trial for Children Without NHS Access Since 2018
Pediatric medical cannabis trials are urgently needed to improve NHS access for children. Despite legalization in 2018, limited clinical evidence restricts treatment availability. Funding these trials will help establish safety and efficacy data for…
CBD Shows Promise, But This Review Warns the Hype Is Outpacing the Science
CBD drug interactions epilepsy present important clinical considerations. Evidence supports CBD's role in epilepsy treatment but warns of risks from drug interactions. Understanding these interactions is vital for patient safety.