Neurological and neurodegenerative conditions, physical activities, and the endocannabinoid system – how might all these be linked?
Can physical activity support the endocannabinoid system in the preventive and therapeutic approach to neurological disorders? In Summary The endocannabinoid signaling system (ECS) of the body includes naturally produced chemicals called cannabinoids,…
Urgent need for clinical trials investigating the effects of cannabinoids on hormone receptor-positive breast cancer therapy
Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment In Summary Breast cancer (BC) is the most common cancer in women worldwide. Approximately 70-80% of BC cases fall into the category of hormone receptor-positive (HR+), which derives its…
Benefits of cannabidiol on skin cells are compromised in psoriasis patients receiving UV irradiation treatment
Cannabidiol Effects on Phospholipid Metabolism in Keratinocytes from Patients with Psoriasis Vulgaris In Summary Endocannabinoid is a group of lipids naturally produced by the body. The endocannabinoid system, which includes mainly endocannabinoids and…
The endocannabinoid system controls various functions of the olfactory circuit
Cannabinoid Control of Olfactory Processes: The Where Matters In Summary: Cannabis exerts its mental and physical effects by producing chemicals called cannabinoids. In mammalian, the endocannabinoid system (ECS) include cannabinoid receptors type 1…
Targeting the endocannabinoid system for stroke prevention
Endocannabinoids and Stroke Prevention: Review of Clinical Studies In Summary Ischemic stroke is a very common medical emergency with 15 million new cases worldwide annually. Its consequences are severe, usually causing permanent disability or even death…
Dysregulation of Fatty Acid Amide Hydrolase Correlates with Increased Obesity
The influence of the fatty acid amide hydrolase 385C_A single nucleotide polymorphisms on obesity susceptibility In Summary A recent study has revealed the positive correlation of fatty acid amine hydrolase (FAAH) polymorphisms with increased obesity…
Saliva Analysis Relates to Diet, Stress, and the Endocannabinoid System
Biological underpinnings from psychosocial stress towards appetite and obesity during youth- research implications towards metagenomics, epigenomics and metabolomics In Summary A recent study has revealed how saliva analysis demonstrates the relationship…
The endocannabinoid system and the placebo effect: Molecular mechanisms of placebo responses in humans
Pain and the placebo effect “The placebo effect” has become somewhat of a buzz word in modern pain management, but what systems actually regulate this effect, and can they be utilized to decrease the need for drugs in a clinical setting?This paper…
Endocannabinoids and stress: Effects of indirect agonists and comparison of male and female mice
Cannabis has stress reducing effects in females as well as males The potential of cannabinoids to treat stress and anxiety is well established, however, previous studies have primarily looked at this effect in males. Here, researchers looked at the…
Do sex and steroid hormones affect cannabis outcomes? A review of the endocannabinoid system
Sex hormones (estrogen, progesterone, and testosterone) substantially impact sexual differentiation, maturation, and adult sexual behavior. The effect of poorly regulated sex hormones affects a significant part of American society, with symptoms ranging…