Does Low-Dose CBD Cause Psychoactive Effects? Findings from a Dose-Dependent Trial
A recent randomized trial investigated dose-dependent side effects cannabinoids by testing oral CBD doses from 20 to 200 mg. The study found only the 200 mg dose produced a small but significant pleasant drug effect, while lower doses did not differ from…
Comparative Pharmacokinetics and Safety of Cannabidiol in a Powder Formulation, CBtru
This study on cbd powder formulation pharmacokinetics reveals comparable bioavailability to traditional oil-based CBD products. It highlights formulation-dependent food effects on absorption in healthy adults. While bioequivalence is established,…
Cannabidiol Inhibits Phenytoin Clearance: Two Clinical Cases
The CBD phenytoin interaction can significantly affect seizure control by altering phenytoin clearance. This case series highlights clinical changes including toxicity and therapeutic benefits. Monitoring phenytoin levels is essential when initiating…
Schedules of Controlled Substances: Temporary Placement of Bromazolam in Schedule I
The temporary placement of bromazolam in Schedule I highlights regulatory efforts to control novel psychoactive substances. This scheduling reflects concerns about bromazolam's abuse potential and lack of accepted medical use. Clinicians should be aware…