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Research validates meconium cannabis testing pregnancy detection as more sensitive than maternal urine for identifying third trimester cannabis exposure. This forensic methodology study provides clinicians with improved detection capabilities for…
Complete radiologic and clinical reversal of lumbar spinal epidural lipomatosis via GLP-1 agonist.
This landmark case demonstrates complete radiologic reversal of severe spinal epidural lipomatosis through GLP-1 agonist-induced weight loss combined with medical cannabis pain management. The patient avoided surgical decompression while achieving…
Cannabis and Mental Health: A Review.
A comprehensive JAMA review reveals the stark gap between widespread cannabis use for mental health conditions and actual clinical evidence. While patients commonly self-medicate with cannabis for psychiatric symptoms, this systematic analysis found…
Prenatal cannabis smoke exposure alters placental development in a murine model of pregnancy.
A new preclinical study demonstrates that prenatal cannabis smoke exposure crosses the placental barrier and disrupts fetal development in mice. This research provides biological evidence supporting clinical recommendations against cannabis use during…
Randomised Controlled Trial Evidence on Medicinal Cannabis for Treatment of Mental Health and Substance Use Disorders: A Scoping Review.
A comprehensive scoping review of randomized controlled trials reveals limited high-quality medicinal cannabis mental health evidence for treating psychiatric and substance use disorders. The systematic review highlights significant gaps in rigorous…
Leveraging NCI’s Collaborative Efforts to Understand Cannabis Use in Cancer
Cannabis use cancer benefits harms are increasingly studied for symptom management among patients with cancer. The National Cancer Institute leads collaborative efforts to evaluate these effects. This research aims to clarify both benefits and potential…
The role of cannabis-based medicinal products (CBMPs) in managing osteoarthritis symptoms: a scoping review of current evidence and future directions.
This review critically evaluates the therapeutic role of cannabis medicinal products osteoarthritis management. It focuses on clinical evidence and efficacy of various pharmacological doses and forms. The findings highlight potential benefits and safety…
IBS Clinical Care Gaps and Future Therapeutics via Peripheral Visceral Afferent Modulation
Peripheral visceral afferent modulation is a promising but unproven approach for IBS pain management. This review highlights the unmet need for safe and effective pain treatment in IBS. Translation from rodent models to human therapeutics remains a…
Evaluating CBD Sleep Product Quality for Effective Use
CBD sleep product quality is essential for ensuring safety and efficacy in sleep support. Clinical evidence for CBD sleep gummies remains limited, emphasizing the need for rigorous evaluation. Patients and clinicians should prioritize third-party lab…
State of Texas: Marijuana Reclassification and Medical Research Expansion
Texas marijuana reclassification could significantly expand medical research by removing regulatory barriers. This change may accelerate evidence-based clinical studies on cannabis therapeutics. Clinicians should monitor evolving research opportunities…