CBD for Anxiety: What 12 Brain-Imaging Studies Actually Show
A 2026 systematic review pooled 12 human neuroimaging studies using fMRI, PET, and SPECT to test whether CBD produces a consistent brain-imaging signature for anxiety and stress. Dr. Caplan walks through why the amygdala findings splinter in both…
Cannabis and Autism: What a 130-Patient UK Registry Study Found
A new UK Medical Cannabis Registry analysis followed 130 autistic adults prescribed cannabis-based medicinal products for 18 months, finding statistically significant improvements in anxiety, sleep quality, and quality of life. Dr. Caplan walks through…
The Polypharmacy Cascade: When Medication Side Effects Are Misdiagnosed as New Illness
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Adolescent Complex Care: Navigating Multi-System Illness and Diagnostic Mysteries
"When an adolescent's illness spans the brain, gut, immune system, and autonomic nervous system, the standard medical model doesn't just struggle—it shatters into disconnected fifteen-minute appointments." There is perhaps no clinical…
Healthcare Governance in the Family Office: The Critical Role of an Independent Medical Quarterback
"Wealth management without healthcare governance leaves families vulnerable to the most consequential blind spot of all: assuming that world-class institutional access is the same as coordinated clinical judgment." Single and multi-family…
Weekly Medical Cannabis & Science Literature Radar: September 13, 2026
A comprehensive weekly literature index analyzing 20 newly published medical cannabis, cannabinoid, and GLP-1 research studies, clinical trial protocols, and regulatory updates.
Cannabis Heart Rhythm, Peer-Reviewed at Last: The JACC Data
The peer-reviewed data behind August's cannabis-and-heart-rhythm headlines are finally out. A randomized JACC trial found modestly less cardiac ectopy on cannabis-use days, but the accompanying editorial warns against reading too much into it. Here is…
Cannabinoids in Mental Health Treatment: A Systematic Review of Efficacy and Safety
Clinical Takeaway Cannabinoids show mixed efficacy in treating mental disorders and substance use disorders with varying safety profiles across studies. Limited evidence supports their use as a primary treatment, highlighting the need for further…
Cannabis Effects on Endocannabinoid System Clinical Research: Cannabidiol’s Impact on Glucose Tolerance and Gut Microbiome
Clinical Takeaway Short-term low-dose cannabidiol did not affect glucose tolerance or alter the gut microbiome in sedentary adults with overweight or obesity. The study found no significant changes in these parameters despite CBD's potential…
Six Million Medical Marijuana Patients: What Sworn DEA
Six million medical marijuana patients is the figure cited in the DEA's marijuana-rescheduling hearing, but sworn testimony argues it reflects registry counts, not physician-supervised clinical evidence. The testimony comes from a company litigating…
