GLP-1 Medications May Quiet the Craving Behind Addiction
A landmark BMJ study published June 3, 2026 found that GLP-1 receptor agonists like semaglutide significantly reduced both the development and severity of substance use disorders in over 600,000 U.S. veterans. Cannabis use disorder risk dropped 14%,…
Modes of cannabis administration, cannabis and tobacco co-use, and associations
This study highlights that adults who co-use cannabis with tobacco are more likely to use combustible methods, leading to worse respiratory outcomes and higher cannabis consumption.
Researchers Identify Genetic Pathways Linking Cannabis Use Disorder and Psychosis Risk
✦ New CED Clinical Relevance #68 Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. ResearchMental HealthNeurologyTHCSafetyPolicyCannabis Use Disorder Why This Matters Clinicians need this genetic…
SAMHSA’s 2026 Clinical Guidance for Physicians and Patients on Cannabis Use Disorder
SAMHSA released a formal 2026 advisory instructing primary care physicians to evaluate cannabis use based on clinical signs of harm, not simply patient use. Dr. Caplan breaks down what this federal guidance actually says, where current diagnostic tools…
In the Mix: 10 More Articles — May 20, 2026
In the Mix — Last 24 HoursMay 20, 2026. 10 articles reviewed below the CED clinical relevance threshold of 35. Listed in descending order of score. #25Treatment delays rising among teens with cannabis use disorder – News-Medical.NetArticle Summary…
Teen cannabis use alters brain development and raises addiction risk – News-Medical.Net
Cannabis effects on teenage brain development present unique clinical concerns during critical neurodevelopmental windows. Adolescent cannabis exposure can disrupt normal brain maturation and increase addiction risk. Understanding these developmental…
Cannabis Use Disorder Clinical Trial Pipeline Gains Momentum
✦ New CED Clinical Relevance #65 Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. ResearchMental HealthSafetyCannabis Use DisorderClinical TrialsTHCPolicy Why This Matters I don't see a summary…
Screaming, vomiting, and daily weed: The rise of ‘scromiting’ among chronic cannabis users
✦ New CED Clinical Relevance #75 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. Mental HealthSafetyResearchTHCNeurologyDosingCannabis Use Disorder Why This Matters I don't see a summary…
Pediatricians warn about cannabis use disorder, kids’ easy access to the drug – YouTube
✦ New CED Clinical Relevance #85 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. PediatricsSafetyPolicyMental HealthResearchTHCCannabis Use Disorder Why This Matters I don't see a summary…
Cannabis Use Disorder Strongly Linked to Major Depression, New Review Finds
✦ New CED Clinical Relevance #78 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. Mental HealthResearchTHCCannabis Use DisorderDepressionSafetyNeurology Why This Matters Clinicians treating patients…