CED Cannabis Science Digest: Key Psychosis and Craving Signals
This digest highlights cannabis psychosis vulnerability signals, focusing on sex-specific risk differences, craving subtypes, and EEG brain-pattern changes in cannabis use disorder. These signals improve psychiatric interpretation without claiming…
Progesterone for Cannabis Use Disorder: What the New Stress-Response Trial Actually Found
A July 2026 trial on progesterone cannabis use disorder research found it reduced stress-linked craving in females. The study was brief and focused on laboratory stress responses. It highlights the need for sex-specific research in cannabis use disorder…
CED Cannabis Science Digest: 3 CUD, Dosing, and Neurobiology Signals Worth Watching
This digest presents 2026 cannabis use disorder research focusing on three key signals: cannabis use disorder recovery biology, THC pharmacokinetic variability, and cannabinoid neurobiology. The included studies provide educational insights without…
GLP-1 Medications May Quiet the Craving Behind Addiction
A landmark BMJ study published June 3, 2026 found that GLP-1 receptor agonists like semaglutide significantly reduced both the development and severity of substance use disorders in over 600,000 U.S. veterans. Cannabis use disorder risk dropped 14%,…
Modes of cannabis administration, cannabis and tobacco co-use, and associations
This study highlights that adults who co-use cannabis with tobacco are more likely to use combustible methods, leading to worse respiratory outcomes and higher cannabis consumption.
SAMHSA’s 2026 Clinical Guidance for Physicians and Patients on Cannabis Use Disorder
SAMHSA released a formal 2026 advisory instructing primary care physicians to evaluate cannabis use based on clinical signs of harm, not simply patient use. Dr. Caplan breaks down what this federal guidance actually says, where current diagnostic tools…
In the Mix: 10 More Articles — May 20, 2026
This article reviews adolescent cannabis use disorder treatment delays and emerging clinical trends in 2026. It highlights the importance of monitoring cannabis mental health impacts in youth. Clinicians should consider regulatory developments affecting…
Teen cannabis use alters brain development and raises addiction risk – News-Medical.Net
Cannabis effects on teenage brain development present unique clinical concerns during critical neurodevelopmental windows. Adolescent cannabis exposure can disrupt normal brain maturation and increase addiction risk. Understanding these developmental…
Cannabis Use Disorder Strongly Linked to Major Depression, New Review Finds
✦ New CED Clinical Relevance #78 Strong Clinical Relevance High-quality evidence with meaningful patient or clinical significance. Mental HealthResearchTHCCannabis Use DisorderDepressionSafetyNeurology Why This Matters Clinicians treating patients…
Teen Substance Use Treatment Evidence
This Evidence Watch article reviews a 2026 systematic evidence update on adolescent substance use treatment. The review found that family-based therapy, CBT, motivational approaches, and multicomponent behavioral care remain the best-supported outpatient…