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PP-01 for Cannabis Withdrawal: What a 14-Person Trial Found
PP-01 for cannabis withdrawal was associated with improved symptom ratings, sleep, and craving in a randomized 14-person crossover trial. The study lasted five nights in an inpatient setting and reported mild adverse events with no serious adverse…
California Study Tracks Adolescent CUD After Cannabis Legalization
Adolescent cannabis use disorder diagnosis trends changed after California legalization passage in a study of 637,461 health-system members aged 13 to 17. The model found different slope changes after passage and retail implementation. The observational…
Cannabis Use Disorder Risk, Internet Use, and Depression: What a Quebec Study Found
cannabis use disorder depression: A cross-sectional Quebec study found that problematic internet use was associated with moderate-to-severe depressive symptoms among adults at high risk for cannabis use disorder. The adjusted association remained after…
The Risks of Medical Cannabis, Counted Honestly: Dependence, Hyperemesis, Heart, Psychosis, Cognition, Driving, and Drug Interactions
The medical cannabis risks and side effects that matter most are the ones with numbers behind them: roughly 22 to 29 percent of users meet criteria for a cannabis use disorder, a third of near-daily smokers surveyed in one emergency department reported…
Cannabis Use Disorder Is Rising Among US Adults
Cannabis use disorder increased among US adult males and females from 2021 through 2024. The national survey also found growth in moderate-to-severe disorder across several age groups. The findings support routine screening but do not identify a cause or…
NY Times Response: Teens and Strong Cannabis
High-potency cannabis risks deserve serious attention, especially for adolescents and frequent users. But potency is not the same as dose, frequent use is not itself addiction, and detectable THC is not synonymous with impairment. A closer reading of the…
Telehealth Plus Mobile Monitoring for Cannabis Use Disorder: MOMENT-V Pilot Trial Launches in Young Adults
MOMENT-V cannabis use disorder trial: A newly published protocol describes a 60-participant pilot randomized trial testing a telehealth-plus-mobile-health intervention for cannabis use disorder in young adults treated in primary care. The trial has not…
Varenicline for Cannabis Use Disorder: What Five Studies Show
Varenicline for cannabis use disorder: A systematic review of five studies involving 299 participants found mixed efficacy and tolerability results. Only one study was rated high quality, and methods were too heterogeneous for meta-analysis. Current…
Insights on Cannabis Craving and Cross-Substance Use from Pooled Trial Data
This pooled analysis of 829 patients examines cannabis craving and cross-substance use, revealing modest, borderline associations with next-week alcohol and cigarette use. The findings highlight the importance of monitoring polysubstance use during…
Are We Over-Diagnosing Cannabis Use Disorder in Prescribed Medical Cannabis Patients?
prescription cannabis use disorder: A new Addiction journal study of 2,054 Australians prescribed medical cannabis found that removing tolerance and withdrawal from Cannabis Use Disorder criteria cut apparent disorder rates among as-prescribed patients…