Why Averages Fail Palliative Cannabis Patients – A New Framework
Randomized controlled trials often fail to capture what palliative care cannabis patients actually experience. A new contextual effectiveness framework argues that averaging subjective outcomes obscures genuine individual benefit. This Evidence Brief…
The Limits of Averages: A Framework for Contextual Effectiveness in Palliative Care Medicinal Cannabis Research.
This article introduces a framework of contextual effectiveness to reconcile the persistent gap between patients' positive experiences with treatments and ne...
Assessments of Evoked and Spontaneous Pain Following Administration of Gabapentin and the Cannabinoid CB
Cannabinoid CB We compared the impact of LY2828360 on evoked and spontaneous pain in a spared nerve injury (SNI) model using a within-subjects design in rats...
Associations Between Cannabis Use and Inflammatory Biomarkers Among People with HIV.
We explored whether self-reported current cannabis use is associated with inflammatory biomarkers among people with HIV (PWH), given high rates of cannabis u...
Unveiling Neurological Benefits: A Review of Hemp Leaf, Flower, Seed Oil Extract, and Their Phytochemical Properties in Neurological Disorders.
Neurological disorders such as epilepsy, Alzheimer's disease, Parkinson's disease, and multiple sclerosis present significant global health care challenges, ...
A Randomized, Open-Label Trial to Assess Feasibility and Tolerability of Topical Cannabis Balms for the Treatment of Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS).
Aromatase inhibitors (AIs) are commonly used for postmenopausal women with hormone receptor-positive breast cancer. Nearly two-thirds of women on AIs have ar...
Regular Cannabis Use is Associated with a Diminished Anandamide Response to a Standard Exercise Stimulus: A Pilot Study.
The endocannabinoid system (ECS) is increasingly recognized as an important regulator of many physiological systems. People who use products derived from Twe...
Medical Cannabis for the Treatment of Peripheral Neuropathy due to Diabetes: A Systematic Review.
This systematic review evaluated randomized controlled trials (RCTs) conducted specifically in participants with diabetes and painful peripheral neuropathy t...
Oral Consumption of Cannabidiol During Pregnancy Alters Behavior in Mouse Offspring.
Pregnant people use cannabidiol (CBD) to treat nausea, insomnia, anxiety, and pain. However, CBD crosses the placenta and enters the fetal brain, where it ca...