Oral Semaglutide for Alcohol Use Disorder: What a New Randomized Trial Found
A phase 2 oral semaglutide alcohol use disorder randomized trial tested 50 adults with moderate to severe alcohol use disorder. The primary craving endpoint was not significantly improved, but several secondary drinking outcomes favored semaglutide.…
Endocannabinoid System & Alcohol Use Disorder: Evidence from Preclinical & Human Studies
The endocannabinoid system alcohol use disorder evidence highlights its role in regulating reward, stress, and emotional processing. Preclinical studies show cannabinoid receptor modulators reduce alcohol intake. However, human trials have shown…
GLP-1 Drugs, Semaglutide, and the Future of Alcohol Addiction Treatment
GLP-1 receptor agonists for alcohol use disorder are attracting growing scientific interest as potential tools for reducing alcohol consumption and relapse risk. This review examines preclinical evidence, observational studies, and randomized controlled…
GLP-1 therapies- an emerging approach for alcohol reduction?
A recent study found that semaglutide significantly reduced heavy drinking days and alcohol craving in adults with alcohol use disorder and obesity, offering a promising new approach.
Once-weekly semaglutide versus placebo in patients with alcohol use disorder and
Semaglutide treatment led to a 13.7 percentage point reduction in heavy drinking days compared to placebo in patients with alcohol use disorder and obesity.
Emerging Clinical Data on GLP-1 Receptor Agonists in Alcohol Use Disorder
GLP-1 receptor agonist alcohol use disorder clinical data reveals potential therapeutic effects beyond glycemic control. This emerging evidence suggests benefits in craving reduction and reward pathway modulation. Family medicine clinicians should…
GLP-1 Drugs for Alcohol Cravings: Clinical Evidence Review
Tirzepatide alcohol cravings reduction is an emerging clinical focus in addiction medicine. This review examines the evidence supporting tirzepatide's effects on alcohol use disorder. Understanding this dual GLP-1/GIP agonist's impact may improve…
Oral Semaglutide and Medicare Coverage: Expanding GLP-1 Access
Oral semaglutide Medicare coverage is expanding access to GLP-1 therapy for patients seeking weight management options. This oral formulation offers an alternative to injections, improving adherence. Understanding Medicare Part D coverage is essential…
Clinical Evidence on Semaglutide for Alcohol Consumption Reduction
Semaglutide alcohol consumption reduction shows promise in clinical trials for patients with alcohol use disorder. This GLP-1 receptor agonist may help reduce heavy drinking days and overall alcohol intake. Understanding this effect is important for…
GLP-1 Receptor Agonist Trial: Semaglutide Reduces Alcohol Cravings
The semaglutide alcohol cravings trial highlights the potential of GLP-1 receptor agonists in reducing alcohol consumption and craving intensity. This study demonstrates semaglutide's role in modulating reward pathways linked to addiction. Semaglutide…