Cannabidiol 20 mg/kg/day and 10 mg/kg/day probably increased the frequency of participants who achieved a ≥50% reduction in monthly seizures (20 mg/kg/day: RR 1.92; 95% CI 1.49–2.46; 10 mg/kg/day: RR 1.94; 95% CI 1.32–2.86, moderate certainty). The incidence of serious adverse events is probably increased with CBD 20 mg/kg/day (RR 2.30; 95% CI 1.36–3.89, moderate certainty).
Association of Multimodal Cannabis Use with Adverse Events among Adolescents and Young Adults.
The ways cannabis is consumed, or modes of use, have increased and diversified in recent years, especially among young people. Associations of multimodal can…
Can CBD Cause Gynaecomastia? Evidence, Hormones, and Safe Use – Bolt Pharmacy
✦ New CED Clinical Relevance #60Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. ⚒ Cannabis News | CED Clinic Endocrine EffectsCbdAdverse EventsMale HealthDrug Safety Why This MattersGynecomastia concerns with CBD could influence prescribing...
Cannabinoids Show Modest, Low-Certainty Benefits for a Few Mental Health Conditions—But Widespread Clinical Use Is Not Justified
Given the scarcity of evidence, the routine use of cannabinoids for the treatment of mental disorders and SUDs is currently rarely justified.