Why a Teenage Brain Is Not a Small Adult Brain: Cannabis, CB1 Receptors, and Cortical Development
Discussions of cannabis and the adolescent brain usually stop at the assertion that it harms development, without saying what the mechanism is or how firm the evidence behind it is. The endocannabinoid system helps organize cortical maturation, and a…
Minnesota Teen Cannabis Use Fell, but Major Social Disparities Persist
Minnesota teen cannabis use fell from 13% in 2013 to 5% in 2025 in statewide student surveys. Important disparities persisted for several groups, including LGBTQ+ youth and youth experiencing poverty. The observational study describes trends but does not…
Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder
Groundbreaking research is investigating adolescent cannabis use disorder biomarkers in the endocannabinoid and opioid systems. This study could identify predictive markers for relapse risk in young patients. The findings may transform how clinicians…
Cannabis Use Disorder and Psychiatric Risk: Why the Findings Deserve a Narrower Reading
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