Skin Layers and Cannabinoid Receptors Diagram
Diagram & reference
A visual reference. The evidence, sources and clinical interpretation are in the linked article.
A visual reference. The evidence, sources and clinical interpretation are in the linked article.
About this diagram
A cross section of skin with receptors labeled where they sit. The block runs from the epidermis at the top through the dermis to the fat layer below, and labels mark CB1, CB2, TRPV1 through TRPV4, TRPA1, PPAR gamma and the endocannabinoids 2-AG and AEA at sensory receptors, nerve endings, immune cells, a hair follicle and a sweat gland. Arrows down each side trace two readings of the same anatomy: physiology to homeostasis on the left, and deregulation in disease to drug targets on the right.
The evidence behind it
Read the evidence: what the mapped skin receptors do and do not tell us about whether cannabis topicals work
That article carries the cited studies, the limits of the evidence, and the clinical interpretation.
That article carries the cited studies, the limits of the evidence, and the clinical interpretation.
