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Endocannabinoid System Research: Cannabis for Endometriosis
Many people with endometriosis use cannabis for symptom relief, but clinical evidence is limited. This medicinal cannabis endometriosis trial evaluated safety and feasibility of inhaled THC and oral CBD oil. The study highlights challenges in conducting…
`Cannabinoid Clinical Trials: CBD and WADA Drug Testing`
Clinical Takeaway Daily use of a broad-spectrum CBD supplement containing trace amounts of other cannabinoids can result in urine concentrations of WADA-prohibited substances such as CBG and CBDV, potentially placing athletes at risk for a positive…
Cannabinoid Clinical Trials: CBD, Psychosis & Brain Function
This study investigates CBD hippocampal glutamate modulation in individuals at clinical high risk for psychosis. Findings reveal CBD influences brain activity during verbal memory tasks. These results highlight CBD's potential neurochemical effects…
Endocannabinoid System Research: Cannabis Use in Pregnancy
Maternal cannabis use in pregnancy is linked to a modestly elevated risk of autism spectrum disorder and ADHD in children. This association is supported by pooled data from multiple observational studies. Current evidence advises caution due to potential…
Cannabis Derivatives for Autism: Clinical Evidence & Research
Several randomized clinical trials have examined cannabis derivatives autism spectrum disorder symptoms. Findings suggest potential benefits for behavioral challenges and social functioning. The evidence base remains limited, so no definitive clinical…
Endocannabinoid System & Teen Anxiety: Clinical Evidence
Internalising symptoms adolescent cannabis use is linked to increased risk of initiation and escalation among teens. This clinical evidence highlights the importance of screening for anxiety and depression in adolescents. Understanding these risks can…
Understanding the Risk of Psychiatric Disorders from Adolescent Cannabis Use
Adolescent cannabis psychiatric disorders risk includes increased chances of psychotic, bipolar, depressive, and anxiety disorders. This risk is supported by large population-level clinical data. Understanding this risk helps guide adolescent mental…
Endocannabinoid System & Trauma Sleep Research Insights
Pre-trauma insomnia and substance use are linked in trauma survivors, increasing risk for problematic alcohol and cannabis use. Early posttraumatic stress symptoms partially mediate this relationship. Addressing sleep disturbances may reduce substance…
Endocannabinoid System Research: Cannabis and PTSD Care
Clinical Takeaway Trauma-focused treatments remain effective for PTSD even when patients report cannabis use alongside co-occurring substance use disorders. Cannabis use does not appear to undermine the clinical benefit of evidence-based, trauma-focused…
Cannabinoids for Chronic Pain: Evidence and Clinical Insights
Cannabinoids for chronic pain evidence indicates modest but consistent pain reduction in randomized controlled trials. Clinical outcomes vary based on product formulation and patient factors. This evidence supports cautious, individualized use in pain…