Cannabinoid Clinical Trials: CBD, Psychosis & Brain Function
This study investigates CBD hippocampal glutamate modulation in individuals at clinical high risk for psychosis. Findings reveal CBD influences brain activity during verbal memory tasks. These results highlight CBD's potential neurochemical effects…
Endocannabinoid System Research: Cannabis Use in Pregnancy
Maternal cannabis use in pregnancy is linked to a modestly elevated risk of autism spectrum disorder and ADHD in children. This association is supported by pooled data from multiple observational studies. Current evidence advises caution due to potential…
Cannabis Derivatives for Autism: Clinical Evidence & Research
Several randomized clinical trials have examined cannabis derivatives autism spectrum disorder symptoms. Findings suggest potential benefits for behavioral challenges and social functioning. The evidence base remains limited, so no definitive clinical…
Endocannabinoid System & Teen Anxiety: Clinical Evidence
Internalising symptoms adolescent cannabis use is linked to increased risk of initiation and escalation among teens. This clinical evidence highlights the importance of screening for anxiety and depression in adolescents. Understanding these risks can…
Endocannabinoid System & Trauma Sleep Research Insights
Pre-trauma insomnia and substance use are linked in trauma survivors, increasing risk for problematic alcohol and cannabis use. Early posttraumatic stress symptoms partially mediate this relationship. Addressing sleep disturbances may reduce substance…
Trauma-Focused Treatment and Cannabis Use in PTSD Care
Trauma-focused treatment PTSD cannabis use remains effective even with co-occurring substance use disorders. Cannabis use does not reduce the benefits of trauma-focused psychotherapy. This insight supports maintaining evidence-based PTSD care protocols.
Change My Mind
Your endocannabinoid system was already mediating pain, mood, and immune function before cannabis became trendy—the plant just happens to be one way to influence it. Further Reading Cannabis NewsRecreational drugs triple the risk of stroke in young…
Tuxedo Winnie the Pooh
“Cannabis is just a plant, can’t be medicine.” Right side fancy Pooh: “Actually, cannabinoids modulate the endocannabinoid system and demonstrate efficacy in peer-reviewed clinical trials for nausea, pain, and seizure…
One Does Not Simply
One does not simply explain the endocannabinoid system to a patient in under fifteen minutes. Further Reading Cannabis NewsRecreational drugs triple the risk of stroke in young people, study finds | The IndependentEvidence WatchDaily Digest 2026-03-08CED…
Cannabinoids for Children: Clinical Evidence Reviewed
Current cannabinoids pediatric safety evidence spans 276 studies covering plant-derived and pharmaceutical formulations for children under 18. This clinical review synthesizes safety and reported benefits from interventional trials and observational…