The Endocannabinoid System Was Here All Along
The body produces its own cannabinoid messengers. In the brain, these signals help adjust communication between nerve cells. Cannabis can act on cannabinoid receptors too, but the endocannabinoid system is part of ordinary physiology even when a person has never used cannabis.
- Lu HC, Mackie K. Review of the Endocannabinoid System. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021;6(6):607-615. doi:10.1016/j.bpsc.2020.07.016. PMID: 32980261.
- Hashimotodani Y, Ohno-Shosaku T, Kano M. Endocannabinoids and synaptic function in the CNS. Neuroscientist. 2007;13(2):127-137. doi:10.1177/1073858406296716. PMID: 17404373.
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