Anticancer Potential of Cannabidiol in Renal Cell Carcinoma: Serum Modulation and Preliminary Mechanistic Insights.
This study explores the anticancer potential cannabidiol renal cell carcinoma effects through serum modulation. Preliminary mechanistic insights provide a foundation for further research. The findings highlight the need for cautious interpretation in…
Advances in Targeting Amyloid Beta Aggregation and Neuroinflammation in Alzheimer’s
Amyloid beta aggregation Alzheimer's disease is a key pathological mechanism driving cognitive decline. This article reviews advances in targeting amyloid beta aggregation and neuroinflammation. Natural products like curcumin show potential but require…
Unraveling Lennox-Gastaut Syndrome: Molecular Pathogenesis and Therapeutic Strategies
Lennox-Gastaut syndrome treatment challenges arise from its complex network dysfunction and drug-resistant seizures. Precision medicine approaches targeting molecular pathways offer new hope. CBD has shown efficacy as adjunctive therapy for this severe…
Factors Associated with Disposable vs Non-Disposable E-Cigarette Use in Adults
Disposable electronic cigarette use has rapidly increased among adults in the U.S. and Israel. This study identifies key factors influencing preferences between disposable and non-disposable devices. Understanding these patterns is essential for…
Cannabidiol Reduces Early-Stage Inflammation in Rat Adipose Tissue
This CBD obesity inflammation study investigates cannabidiol's impact on fat tissue inflammation in rats. The research highlights CBD's potential to reduce lipid accumulation and inflammatory markers. Findings suggest tissue-specific effects in visceral…
Unregulated Substance Abuse and Systemic Inflammation Markers: A Review.
This review examines inflammatory biomarkers unregulated substance use and their impact on systemic inflammation. It highlights the clinical relevance of monitoring these markers in patients with polysubstance use. Understanding these biomarkers aids…
A Novel Adverse Outcome Pathway in Aluminum-Induced Male Infertility
Oxidative stress male infertility is a critical focus in understanding aluminum's reproductive toxicity. This study reveals how aluminum triggers endoplasmic reticulum stress and disrupts the endocannabinoid system. These findings provide new insights…
Lifestyle and Behavioral Enhancements of Sleep: A Review
Sleep hygiene CBT-I is a cornerstone of behavioral interventions for sleep disorders, offering evidence-based lifestyle enhancements. This review highlights the importance of non-pharmacological therapies in improving sleep quality sustainably.…
Nationwide Outcomes of Cardiac Surgery in Patients with Cannabis Use Disorder
This study evaluates cannabis use disorder cardiac surgery outcomes using a nationwide database. Findings show no increased in-hospital morbidity or mortality linked to cannabis use disorder. The research highlights the importance of assessing…
Anesthesia Needs for Cannabis Users During Wisdom Tooth Surgery
Propofol dosing cannabis users require during third molar removal under intravenous anesthesia may be higher than nonusers. This study highlights the need for tailored anesthetic management in cannabis-exposed patients. Understanding propofol dosing…