Evaluating Cannabis Substitution for Alcohol in a Canadian MAP
Cannabis substitution alcohol harm reduction is being evaluated within Canadian managed alcohol programs. This approach offers a potential lower-risk alternative for individuals with severe alcohol use disorder. The study provides early evidence…
Trends from the Rhode Island Harm Reduction Surveillance System: 2021-2024
This report highlights harm reduction polysubstance use disability trends in Rhode Island from 2021-2024. Cannabis use is prevalent among high-risk populations with disabilities. Understanding these patterns is critical for effective clinical…
Changes in Levels of Endocannabinoidome Mediators in Mice with Cancer Cachexia
Cancer cachexia involves significant changes in the endocannabinoid system cancer cachexia mediators, affecting metabolism and gut health. This study in mice reveals links between these mediators and steatosis as well as gut microbial dysbiosis.…
Endocannabinoids and Polyunsaturated Fatty Acids in Early Schizophrenia: Changes Under Antipsychotics and Treatment Response
The endocannabinoid system schizophrenia alterations are evident in early stages of the disorder. This study highlights changes in polyunsaturated fatty acids and endocannabinoids before and after antipsychotic treatment. Understanding these biochemical…
Reasons for Cannabis Use Among Adults with Disabilities: Insights from the 2023-2024 Survey
Cannabis use among adults with disabilities is notably higher than in the general population. The 2023-2024 National Survey on Health and Disabilities reveals key reasons for this trend. Understanding cannabis use among adults with disabilities is…
Is cannabis legalization associated with treatment completion? A study of pregnant women admitted for cannabis use in substance use treatment facilities, 2020-2022.
Pregnant women cannabis treatment completion is a critical measure in understanding recovery success amid evolving legalization. This study analyzes treatment completion rates for pregnant women admitted for cannabis use disorder from 2020 to 2022.…
The quality and scope of health information on online drug platforms: a topic modelling and expert evaluation study of a Polish-language forum.
This study evaluates health information quality online drug platforms, focusing on user-generated content from a Polish-language forum. It reveals how cannabis users discuss symptom relief and inflammation management. Understanding this quality is…
Therapeutic Potential and Pharmacological Mechanisms of Cannabinoids in Alleviating Chemotherapy-Induced Organ Toxicity
Cannabinoids chemotherapy organ protection research highlights their potential to reduce organ toxicities caused by chemotherapy. These include cardiotoxicity, nephrotoxicity, hepatotoxicity, and neurotoxicity. Understanding pharmacological mechanisms is…
Unraveling Endocannabinoid Signaling Pathways in Cisplatin-Induced Ototoxicity
Cisplatin-induced ototoxicity is a detrimental side effect of chemotherapy leading to hearing loss, for which no treatments are currently available. This study reveals the presence of endocannabinoid signaling pathways in auditory hair cells affected by…
Standardizing Recreational Cannabis Excise Tax Rates in the United States: New Retail Price-Based Measurements by Product Category
Standardized cannabis excise tax rates reveal significant variation across product categories and states. Understanding these tax burdens is crucial for clinicians advising patients on cost-effective cannabis therapy. This analysis highlights the impact…