Attitudes, Beliefs and Willingness to Prescribe Medical Cannabis Among Public Medical Practitioners in Malaysia
This survey highlights physician attitudes medical cannabis Malaysia, showing 65% support among public medical practitioners. Pain management, particularly cancer pain, is the leading indication for prescribing willingness. These findings provide…
Innovative Aptamer-Based Liquid Sensing Display for Label-Free Detection
This study introduces an aptamer-based liquid sensing display for label-free THC detection. The technology integrates with smartphones for rapid, point-of-care analysis. Aptamer-based liquid sensing display offers a novel approach to illicit substance…
Letter by Wu et al Regarding Article, “G Protein-Coupled Receptor Kinase 3 Exacerbates Diabetic Heart Injuries Through Direct Phosphorylation of Cannabinoid Receptor 2 in Humans and Mice”.
This letter discusses cannabinoid receptor 2 phosphorylation and its role in diabetic heart injury. The phosphorylation by GRK3 may impair CB2 receptor function in diabetes. Understanding cannabinoid receptor 2 phosphorylation is key to future diabetic…
Mobile App-Based Study of Driving Behaviors Under Cannabis Influence
This study investigates cannabis driving impairment using smartphone sensors to detect real-world driving behavior changes. It highlights key impairment indicators such as weaving, wide turning, and hard braking. The findings provide early-stage evidence…
Behavioural, Pharmacokinetic, and Genetic Evidence of CBD-Oxycodone Interaction in Mice
This study investigated cannabidiol oxycodone interaction and its effects on opioid analgesia and pharmacokinetics. Acute CBD administration increased oxycodone exposure and analgesic duration. Chronic use accelerated tolerance development specific to…
Medically Recommended Cannabis Use for US Adolescents.
This study examines medically recommended cannabis use adolescents using nationally representative data. It reveals 5.2% of adolescent cannabis users have medical recommendations. Understanding medically recommended cannabis use adolescents informs…
Unlocking the Multifaceted Role of CB
CB1 receptor pharmacology research reveals the complex signaling of the endocannabinoid system. This complexity explains the challenges in developing cannabinoid therapeutics. Understanding CB1 receptor roles is key to advancing clinical outcomes.
Cannabidiphorol (CBDP) as a Negative Allosteric Modulator at CB1
This article discusses minor cannabinoids CB1 receptors preclinical research focusing on cannabidiphorol (CBDP). CBDP acts as a negative allosteric modulator at two distinct sites of the CB1 receptor. Understanding this modulation is crucial for future…
Cannabidiol in Developmental Epilepsy: Organoid-Guided Precision Medicine Across Critical Neurodevelopmental Windows.
CBD neurodevelopmental epilepsy research reveals promising precision medicine approaches targeting critical developmental windows. This review synthesizes evidence on CBD's neuroprotective and antiseizure effects in pediatric epilepsy. Understanding…
Understanding Neurotransmitter Systems in Alzheimer’s Disease
Neurotransmitter systems Alzheimer's disease dysfunction plays a key role in cognitive decline. Multiple systems including cholinergic, glutamatergic, and GABAergic are affected. Understanding these systems helps explain treatment challenges.