Brain-Body Integromics of the Ayahuasca Experience
Brain-body integration ayahuasca effects reveal how this psychoactive brew induces coordinated changes across biological systems. This study maps metabolism, brain connectivity, and subjective experience in ayahuasca users. Understanding these effects is…
Mechanistic Pathways Linking Cannabidiol, Hemp Seed Oil and Black Sesame Oil in Hyperarousal Insomnia: A Narrative Review.
This narrative review explores mechanistic pathways insomnia involving cannabidiol, hemp seed oil, and black sesame oil. It highlights how these compounds may modulate hyperarousal insomnia through multiple biological pathways. Understanding these…
Characterizing Public Comments on Cannabis Rescheduling via Regulations.gov
This study analyzes cannabis rescheduling public comments submitted to Regulations.gov in 2024. Over 42,000 comments reveal diverse stakeholder perspectives on DEA's proposed Schedule III change. Understanding these comments helps clinicians anticipate…
Neuropathic Pain Severity Linked to Opioid Use in Adults with Traumatic SCI
This study investigates opioid use neuropathic pain spinal cord injury relationships in adults with traumatic SCI. Findings highlight employment as protective against opioid use. Multimodal approaches including cannabis are common in severe neuropathic…
Pediatric Hemp-Derived Cannabinoid and Δ9-THC Exposures: A National Poison Data Study.
This study examines pediatric hemp-derived cannabinoid exposures, focusing on unintentional ingestion risks in children. It highlights increased toxicity compared to Δ9-THC. The findings emphasize the need for awareness and clinical vigilance.
Regional (In)Consistency and Comparability of Cannabis Laboratory Testing: A Statistical Exploration of Total Yeast and Mold
Cannabis laboratory testing variability significantly impacts product safety and patient health. This study explores yeast and mold contamination across state testing protocols. Understanding these differences is crucial for ensuring consistent cannabis…
Cannabidiol Synergizes with Methotrexate to Attenuate Rheumatoid Arthritis
The cbd methotrexate combination rheumatoid arthritis approach shows promise in preclinical studies. This combination targets STAT3/NF-κB signaling to reduce inflammation. Further human trials are needed to confirm safety and efficacy.
Patient Perspectives on Non-Traumatic Painful Upper-Extremity Conditions and Substance Use
This study explored patient experiences with non traumatic painful upper extremity conditions and co-occurring risky substance use. It assessed perspectives on integrated web-based mind-body interventions addressing both conditions. Findings highlight…
Impact of Combined Cannabinoids and Cocaine on Trauma Outcomes
This study investigates combined cannabinoids cocaine trauma outcomes in trauma patients. It analyzes mortality and clinical endpoints using a large trauma registry. Understanding these outcomes aids trauma care planning and substance use counseling.
Classic psychedelic and cannabis use among U.S. cancer survivors aged ≥ 50 years: nationally representative estimates by cancer type/site.
This study examines classic psychedelic and cannabis use among older cancer survivors aged 50 years and above. It provides nationally representative estimates by cancer type and site. Understanding these patterns is crucial for clinical and policy…