Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms
A groundbreaking clinical trial is investigating stress induced opioid misuse mechanisms in chronic back pain patients by examining how acute stress modulates endogenous opioid and endocannabinoid systems. This research could identify biomarkers that…
Unpredictable Chronic Mild Stress Upregulates Dopamine Receptor Expression Independent of Fatty Acid-Binding Protein 7 Gene Deletion.
Fatty acid-binding protein 7 (FABP7) assists in the intracellular trafficking of endogenous cannabinoids and polyunsaturated fatty acids (PUFAs) and has been...
Unpredictable Chronic Mild Stress Upregulates Dopamine Receptor Expression Independent of FABP7
This study investigates chronic mild stress dopamine receptor expression and its independence from FABP7 gene deletion. Findings reveal increased dopamine receptor levels under stress regardless of FABP7 status. Understanding chronic mild stress dopamine…
West-Asia War Impact: IDF Strikes and Psychological Stress
Military conflicts and psychological stress significantly impact mental health, especially PTSD and anxiety. Cannabis medicine may help manage acute stress responses during such events. Understanding this relationship is crucial for vulnerable…
Tecan Webinar Shares Insights on Salivary Cortisol, from Collection to Confidence
Salivary cortisol measurement cannabis protocols offer a non-invasive way to assess stress response in patients using cannabis therapeutically. This webinar highlights improved collection and analysis methods to enhance reliability. Understanding these…
Selective Upregulation of FABP5 in Amygdala Reduces Cocaine-Seeking
This study highlights the endocannabinoid system cocaine addiction treatment potential by examining FABP5 upregulation in the basolateral amygdala. Anandamide's role in reducing stress-induced cocaine-seeking behavior is central to this research. These…
Personalized Resilience: Variability in Brain-Immune Stress Responses
Brain-immune responses to stress vary significantly among individuals, influencing anxiety disorder development. This variability affects HPA axis regulation and immune function. Understanding these responses is key to personalized resilience strategies.