Clinical Takeaway Adolescent cannabis use is associated with significantly increased risk of developing psychotic, bipolar, depressive, and anxiety disorders in adolescence and young adulthood, based on large-scale longitudinal population data. These findings...
Adolescent Cannabis Use and Mental Health: Clinical Evidence
Clinical Takeaway Large-scale longitudinal data show that adolescent cannabis use is associated with increased risk of developing psychotic, bipolar, depressive, and anxiety disorders into young adulthood. These are clinically diagnosed conditions, not...
Large Genetic Meta-Analysis Finds Endocannabinoid Pathway Variants Linked to Shared Psychiatric Risk
We identified nine SNPs significantly associated with a change in risk of having a mental disorder. The lead SNP was rs12805732 (Gene: Diacylglycerol Lipase Alpha; DAGLA). Four SNPs had substantial heterogeneity (I²>60%). DAGLA had the strongest association with disease risk in gene-based analysis.
Endocannabinoid System & GLP-1 Receptor Mental Health Evidence
Clinical Takeaway GLP-1 receptor agonists, the drug class that includes medications like semaglutide, were studied for their potential causal effects on ten common mental health conditions using genetic analysis data. The findings...
5 Surprising Benefits of Cannabidiol Anxiety Treatment
Exploring the Benefits and Safety of Nano-particle CBD for Anxiety Treatment What is this All About? Anxiety disorders are some of the most common mental health issues around the world. In 2019,...