A prospective study found that cannabis users with 2-3 years of regular use required significantly higher propofol doses during third molar surgery. This research provides evidence-based risk stratification for cannabis anesthesia requirements oral surgery planning and highlights the importance of disclosure for patient safety.
Cannabis Users Need More Propofol, But Confounders Cloud the Evidence
Propofol requirements were significantly higher in cannabis users, who required an average additional dose of 47.33 mg compared to non-users. Subgroup analyses revealed that cannabis users undergoing general anesthesia needed an additional 30.57 mg intraoperatively, while those undergoing sedation for endoscopic procedures required an additional 53.02 mg.