Cannabinoids in Mental Health Treatment: A Systematic Review and Meta-Analysis
Clinical Takeaway Randomized controlled trial evidence shows limited and inconsistent support for cannabinoids as a primary treatment for mental health or substance use disorders. Adverse effects were commonly reported across studies, raising important…
Cannabinoid Chewing Gum: Promising Concept, Thin Evidence
Despite a long-standing widespread history of chewing gum use in general, there is sparse experience and even less clinical research on the effects and possible clinical value of incorporating cannabidiol or any other cannabinoid in a chewing gum product.
CBD Chewing Gum: Promising Concept, Thin Evidence
Despite promising reports, research gaps remain, particularly in understanding the absorption mechanisms, dosing precision, and long-term safety of cannabinoid-based chewing gum.
Cannabis Oil Did Not Meaningfully Reduce Pain in Nerve-Injury Patients, Rigorous Trial Finds
Our study findings indicate that cannabis-based medicine did not improve pain by a clinically important margin. Consequently, our study advises against the addition of cannabis-based medicine to the standard medication treatment for pain in patients with…
Expert Commentary Backs Negative Cannabis Trial for Brachial Plexus Pain
These negative results based on solid evidence will help surgeons to avoid raising false hopes and circumvent the use of futile therapies.
`Cannabinoid Clinical Trials: CBD vs Placebo in Fibromyalgia`
Clinical Takeaway In this randomized, double-blind, placebo-controlled trial, CBD did not demonstrate superiority over placebo in reducing pain among patients with fibromyalgia. The findings add to a growing body of evidence suggesting that CBD alone may…
cannabinoid clinical trials: CBD vs Placebo Fibromyalgia
Clinical Takeaway In this randomized, double-blind, placebo-controlled trial, CBD did not demonstrate superiority over placebo in reducing pain among patients with fibromyalgia. The findings do not support CBD as an effective standalone treatment for…
`Cannabinoids for PTSD and Substance Use: Clinical Evidence`
Clinical Takeaway Trauma-focused treatments remain effective for PTSD even in patients who use cannabis, including those with co-occurring substance use disorders. Cannabis use at baseline does not appear to undermine the clinical benefits of…
Endocannabinoid System Research: Cannabis & PTSD Treatment
Clinical Takeaway People with PTSD and co-occurring substance use disorders who also use cannabis can still benefit meaningfully from trauma-focused treatments. Cannabis use does not appear to prevent or significantly undermine the effectiveness of…
Endocannabinoid System Research: Cannabis and PTSD Care
Clinical Takeaway Trauma-focused treatments remain effective for PTSD even when patients report cannabis use alongside co-occurring substance use disorders. Cannabis use does not appear to undermine the clinical benefit of evidence-based, trauma-focused…