# Study: Teen Cannabis Use Linked to Double Psychosis Risk

> **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637)
> **Publisher:** CED Clinic (https://cedclinic.com)
> **Canonical URL:** https://cedclinic.com/teen-cannabis-use-psychosis-risk-study/
> **Published:** 2026-02-23T13:02:03-04:00 | **Last Modified / Clinically Audited:** 2026-09-28T11:14:40-04:00
> **Clinical Summary:** Explore the teen cannabis use psychosis risk revealed by a large study linking adolescent cannabis use to doubled psychotic and bipolar disorder risk.

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CED Clinical Relevance#75 Strong Clinical RelevanceHigh-quality evidence with meaningful patient or clinical significance.



Mental HealthTHCPediatricsPolicy



Why This MattersThis is one of the largest studies ever conducted on teen [cannabis use](https://cedclinic.com/cannabis-cardiovascular-health-insights-2024/) and psychiatric outcomes, and it reinforces that age restrictions and youth prevention should be central to any legalization framework.



Clinical Summary

A JAMA Health Forum study of 463,396 adolescents ages 13 to 17 found cannabis use was linked to a twofold increase in psychotic and [bipolar disorder](https://cedclinic.com/cannabis-induced-appetite-satiety-bypass-thc-brain/) risk by age 26. The study represents one of the largest longitudinal investigations of this association, drawing on clinical health records rather than self-reported data. Researchers note that the findings reinforce the need for youth-focused prevention strategies regardless of the broader legalization debate.






Dr. Caplan’s Take“This study doesn’t argue against legalization, it argues for honest, evidence-based youth prevention as a non-negotiable component of any responsible cannabis policy.”



Clinical Perspective


A landmark JAMA Health Forum study tracking nearly half a million adolescents reveals a twofold increased risk of psychotic and bipolar disorders among cannabis users by age 26. Drawing on actual clinical records rather than self-reported data, this longitudinal research offers compelling evidence for conversations about adolescent neurodevelopment and substance use.







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For readers who would like a deeper examination of the study’s methodology, statistical framing, and what these findings do and do not establish clinically, Dr Caplan has published a detailed clinical review of the original JAMA Health Forum paper here: [Adolescent Cannabis Use and Psychosis Risk – Study Review](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/).



Related Articles


- [Kaiser Study Finds Higher Risk of Psychiatric Disorders in Teens Who Use Cannabis](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)

- [Teenage Cannabis Users Twice as Likely as Non-Users to Develop Psychosis](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)




 

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📰 Source: [https://ground.news/daily-briefing/study-teen-cannabis-use-linked-to-d](https://ground.news/daily-briefing/study-teen-cannabis-use-linked-to-d)

 Further Reading
 Evidence Watch[Endocannabinoid System Research: Cannabinoids in Pediatric Care](https://cedclinic.com/cannabinoid-clinical-trials-pediatric-care-research/)CED Clinic Blog[Adolescent Cannabis Use and Psychosis Risk: What This Cohort Study Shows and What It Does Not](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)Cannabis Memes[College is hard lmao](https://cedclinic.com/college-is-hard-lmao/)

 
 
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RELATED READING AT CED CLINIC

Continue exploring the evidence

[Endocannabinoid System Research: Teen Cannabis and Mental Health](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)

Explore research on how the [endocannabinoid system](https://cedclinic.com/endocannabinoid-system-fear-extinction/) relates to teen cannabis use and its impact on mental health.

[Read More](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)

[Adolescent Cannabis Use Linked to Doubling Risk of Psychotic and Bipolar Disorders](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)

A detailed look at the increased risk of psychotic and bipolar disorders linked to adolescent cannabis use.

[Learn More](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)

[Teenage Cannabis Users Twice as Likely as Non-Users to Develop Psychosis](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)

Study findings show teenage cannabis users have twice the risk of developing psychosis compared to non-users.

[Discover Insights](https://cedclinic.com/adolescent-cannabis-psychiatric-outcomes-2026-digest/)

 

### Related

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### Verification & Medical Governance

- **Lead Clinical Author:** Benjamin Caplan, MD
- **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House).
- **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`).
- **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/).
- **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637).
- **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).
