# CORR Insights®: Does Cannabis-based Medicine Improve Pain and Sleep Quality in Patients With Traumatic Brachial Plexus Injuries? A Triple-blind, Crossover, Randomized Controlled Trial

> **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637)
> **Publisher:** CED Clinic (https://cedclinic.com)
> **Canonical URL:** https://cedclinic.com/research/cannabis-for-pain-randomized-controlled-trial/
> **Published:** 2026-10-26T11:14:11-04:00 | **Last Modified / Clinically Audited:** 2026-10-26T11:14:11-04:00
> **Clinical Summary:** Researchers evaluated whether adding plant-derived cannabis drops to standard medical treatment would improve chronic nerve pain and sleep for adult men.

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This is a commentary on the article by Kittithamvongs et al. exploring the use of cannabis-based medicine as an adjuvant to multimodal drug therapy in the setting of neuropathic pain related to severe traumatic brachial plexus injuries. The commentary discusses the methodology and findings of the triple-blind, crossover, randomized controlled trial involving 28 matched male patients who received cannabis drops versus placebo. The study found no clinically important benefit of cannabis-based treatment as an adjuvant to standard multimodal drug therapy for this specific patient population.

 

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### Verification & Medical Governance

- **Lead Clinical Author:** Benjamin Caplan, MD
- **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House).
- **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`).
- **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/).
- **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637).
- **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).