# Project Twenty21 Australia finds year-long improvements in pain and anxiety > **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637) > **Publisher:** CED Clinic (https://cedclinic.com) > **Canonical URL:** https://cedclinic.com/project-twenty21-australia-finds-year-long-improvements-in-pain-and-anxiety/ > **Published:** 2026-09-07T12:23:42-04:00 | **Last Modified / Clinically Audited:** 2026-09-28T10:45:22-04:00 > **Clinical Summary:** Project Twenty21 Australia finds year-long improvements in chronic pain and anxiety with medicinal cannabis, supporting long-term treatment options. --- ✦ New CED Clinical Relevance #67 Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. PainAnxietyMental HealthResearchPolicySafetyDosing Why This Matters This article signifies significant advancements in the field of medicinal cannabis, as it provides evidence supporting long-term benefits for chronic pain and anxiety management. These findings could potentially influence clinicians’ decisions when considering cannabis-based treatments for their patients suffering from these conditions, thereby improving overall patient care and quality of life. Clinical Summary In a study by Project Twenty21 Australia, it was observed that patients with chronic pain and anxiety experienced sustained improvements over a period of twelve months while using medicinal cannabis. This finding suggests potential long-term benefits for these conditions when treated with medicinal cannabis, which may be relevant for clinicians managing such patients. Dr. Caplan’s Take “As a seasoned family physician specializing in cannabis medicine, the findings from Project Twenty21 Australia are indeed encouraging. A year-long improvement in chronic pain and anxiety among medicinal cannabis patients is noteworthy, suggesting potential long-term benefits. However, it’s crucial to acknowledge that this observational study requires peer review for validation, as with any research in this evolving field.” Clinical Perspective 💊 🌱 A recent study, Project Twenty21 Australia, reports sustained improvements in chronic pain and anxiety symptoms among medicinal cannabis patients over a 12-month period. This research adds to the growing body of evidence suggesting potential benefits for certain patient populations. However, it’s crucial to acknowledge the complexity of individual responses to cannabis-based treatments due to factors such as strain variability, dosage, and patient comorbidities. In clinical practice, healthcare providers should consider these findings when discussing treatment options with patients experiencing chronic pain and anxiety, but always with a cautious approach, emphasizing the need for ongoing monitoring and adjustment of therapy based on individual responses. 💬 Join the Conversation Have a question about how this applies to your situation? [Ask Dr. Caplan →](https://benjamincaplan.com/ask-dr-caplan) Want to discuss this topic with other patients and caregivers? [Join the forum discussion →](https://cedclinic.com/interact/discussion-forums/forum/pain-management/) Have thoughts on this? 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