# Cytokine Storm Flowchart With THC and CBD

> **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637)
> **Publisher:** CED Clinic (https://cedclinic.com)
> **Canonical URL:** https://cedclinic.com/d65-thc-cbd-and-cytokine-storms-png/
> **Published:** 2026-09-04T23:01:44-04:00 | **Last Modified / Clinically Audited:** 2026-09-13T14:37:52-04:00
> **Clinical Summary:** How THC, CBD, anandamide, and 2-AG act on the cytokines behind cytokine storms, with a comparison table of cannabinoid effects on cytokines.

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[← Back to the Tables Summary Hub](https://cedclinic.com/topic-tables/)Diagram & referenceA visual reference. The evidence, sources and clinical interpretation are in the linked article.About this diagramA six step flowchart read from the top down. It runs from a cytokine storm, to an overactive immune response, to pro-inflammatory cytokines, to IL-6 specifically, then to the point where THC and CBD interact, and ends at possible modulation of the immune response. The final two boxes are where the cannabinoids enter the sequence; everything above them is standard immunology. The last box is written as a possibility, not a demonstrated outcome.The evidence behind it[Read the evidence: the laboratory signal, and the one negative randomized human trial](https://cedclinic.com/cannabinoids-and-cytokine-storm-evidence-review/)That article carries the cited studies, the limits of the evidence, and the clinical interpretation.

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### Verification & Medical Governance

- **Lead Clinical Author:** Benjamin Caplan, MD
- **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House).
- **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`).
- **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/).
- **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637).
- **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).