# THC Bioavailability Chart by Route

> **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637)
> **Publisher:** CED Clinic (https://cedclinic.com)
> **Canonical URL:** https://cedclinic.com/d42-png-application-method-vs-thc-plasma-concentration-topical-oral-pulmonary/
> **Published:** 2026-09-04T23:02:10-04:00 | **Last Modified / Clinically Audited:** 2026-09-13T14:39:04-04:00
> **Clinical Summary:** How topical, oral, and pulmonary administration change THC plasma concentration, with a comparative analysis and special medical considerations.

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[← Back to the Timing Summary Hub](https://cedclinic.com/topic-timing/)Diagram & referenceA visual reference. The evidence, sources and clinical interpretation are in the linked article.About this diagramA three bar chart comparing THC blood plasma concentration after topical, oral, and pulmonary use, with a dashed reference line drawn low on the scale. The topical bar sits below that line, the oral bar rises to roughly a third of the plotted range, and the pulmonary bar is the tallest by a wide margin. Read the relative heights rather than the axis numbers, because the vertical scale is printed without units and the figure names no source for the values.The evidence behind it[Read the evidence: measured cannabinoid exposure from inhaled, oral, and topical products](https://cedclinic.com/how-much-thc-gets-into-your-blood-by-method/)That article carries the cited studies, the limits of the evidence, and the clinical interpretation.

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### Verification & Medical Governance

- **Lead Clinical Author:** Benjamin Caplan, MD
- **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House).
- **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`).
- **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/).
- **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637).
- **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).