# Comparative efficacy of non-pharmacological interventions for individuals with cannabis use disorder

> **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637)
> **Publisher:** CED Clinic (https://cedclinic.com)
> **Canonical URL:** https://cedclinic.com/comparative-efficacy-of-non-pharmacological-interventions-for-individuals-with-cannabis-use-disorder-2/
> **Published:** 2026-08-22T17:18:58-04:00 | **Last Modified / Clinically Audited:** 2026-09-08T20:15:52-04:00
> **Clinical Summary:** Explore the efficacy of cognitive-behavioral therapy in treating cannabis use disorder, as highlighted by recent Global Burden of Disease analyses.

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✦ New

CED Clinical Relevance
#72
Notable Clinical Interest
Emerging findings or policy developments worth monitoring closely.

Mental HealthAnxietyNeurologyPolicyResearchDosingSafety

Why This Matters
This article matters to clinicians and their patients because it provides evidence on the effectiveness of non-pharmacological interventions for individuals with [Cannabis Use Disorder](https://cedclinic.com/sex-differences-cannabis-stress-reactivity-oxytocin/). As cannabis is identified as the most prevalent drug causing substance-related disorders globally, understanding these interventions can aid in improving treatment strategies, thereby enhancing [patient care](https://cedclinic.com/cannabis-cardiovascular-risk-impact/) and recovery. The findings from this study could potentially guide clinicians in selecting appropriate interventions tailored to individual patients’ needs, ultimately contributing to better clinical outcomes.

Clinical Summary

This study compares the effectiveness of non-pharmacological interventions for individuals with [cannabis use](https://cedclinic.com/cannabis-cardiovascular-health-insights-2024/) disorder. The research reveals that cognitive behavioral therapy (CBT) and motivational enhancement therapy (MET) are particularly effective in reducing [cannabis use](https://cedclinic.com/cannabis-cardiovascular-health-insights-2024/). For clinicians, these findings suggest considering CBT and MET as potential treatment options for patients struggling with [cannabis use disorder](https://cedclinic.com/sex-differences-cannabis-stress-reactivity-oxytocin/).

Dr. Caplan’s Take
“The latest research suggests a promising shift towards non-pharmacological approaches for managing [Cannabis Use Disorder](https://cedclinic.com/sex-differences-cannabis-stress-reactivity-oxytocin/). However, it’s crucial to acknowledge that these findings are preliminary and require further replication in human studies before we can confidently integrate them into [clinical practice](https://cedclinic.com/cannabis-reproductive-health-women-clinical-evidence/).”

– [Dr. Benjamin Caplan](https://cedclinic.com/cannabis-halloween-safety/), MD

Clinical Perspective

🔬 In a recent study titled “Comparative efficacy of non-pharmacological interventions for individuals with [cannabis use](https://cedclinic.com/cannabis-cardiovascular-health-insights-2024/) disorder,” findings suggest that various non-drug approaches may offer relief. However, it’s crucial to acknowledge the complexity in implementing these strategies due to factors like individual differences, treatment settings, and cultural variations. While more research is needed to confirm these results, healthcare providers might consider incorporating cognitive behavioral therapy, motivational interviewing, and family therapy as potential adjuncts to traditional care for managing cannabis use disorder. 🤝

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📰 Source: [https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0355941&type=printable](https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0355941&type=printable)

Further Reading
CED Clinic Blog[Why Cannabis Works](https://cedclinic.com/why-cannabis-works/)
Evidence Watch[Cannabis and Heart Health](https://cedclinic.com/cannabis-cardiovascular-health-study/)
CED Clinic Blog[Cannabis for Sleep](https://cedclinic.com/cannabis-for-sleep/)

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### Related

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### Verification & Medical Governance

- **Lead Clinical Author:** Benjamin Caplan, MD
- **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House).
- **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`).
- **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/).
- **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637).
- **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).
