# Research Shows a Popular Anti-Aging Supplement May Lower Blood Pressure > **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637) > **Publisher:** CED Clinic (https://cedclinic.com) > **Canonical URL:** https://cedclinic.com/cardiovascular-drug-interactions-cannabis-supplements/ > **Published:** 2026-04-07T14:03:31-04:00 | **Last Modified / Clinically Audited:** 2026-09-28T10:28:15-04:00 > **Clinical Summary:** Explore cardiovascular drug interactions between cannabis and popular supplements like NMN that may affect blood pressure and patient safety. --- ✦ New CED Clinical Relevance  #70Notable Clinical Interest  Emerging findings or policy developments worth monitoring closely. ⚒ Cannabis News  |  CED Clinic CardiovascularDrug InteractionsSupplementsBlood PressurePatient Safety Why This Matters While this appears to be about NMN (nicotinamide mononucleotide) rather than cannabis, cardiovascular effects are a critical consideration for [cannabis prescribing](https://cedclinic.com/addressing-cannabis-education-gap-clinical-care/). Cannabis can affect blood pressure through various mechanisms, and understanding interactions with popular supplements becomes relevant when treating patients using both therapies. Clinical Summary The referenced article discusses NMN, an anti-aging supplement, not [cannabis medicine](https://cedclinic.com/essential-oils-industrial-hemp-antimicrobial-benefits/). However, for cannabis clinicians, cardiovascular interactions remain paramount. Cannabis can cause orthostatic hypotension acutely and may have varied longer-term cardiovascular effects depending on consumption method, dosing, and individual patient factors. Patients often use multiple supplements alongside [cannabis therapy](https://cedclinic.com/cannabis-based-therapies-smoking-cessation/). Dr. Caplan’s Take “This highlights why I always ask patients about their complete supplement regimen — interactions between cannabis and popular wellness supplements like NMN aren’t well-studied, but cardiovascular effects can compound unpredictably.” Clinical Perspective 🧠 Clinicians should maintain comprehensive medication and supplement histories for cannabis patients, particularly those with cardiovascular concerns. Monitor blood pressure when initiating [cannabis therapy](https://cedclinic.com/cannabis-based-therapies-smoking-cessation/), especially in patients using other vasoactive substances. The supplement-cannabis interaction landscape remains largely unstudied. 💬 Join the Conversation Have a question about how this applies to your situation? [Ask Dr. Caplan →](https://benjamincaplan.com/ask-dr-caplan) Want to discuss this topic with other patients and caregivers? [Join the forum discussion →](https://cedclinic.com/interact/discussion-forums/forum/cannabis-industry/) Have thoughts on this? Share it: [𝕏 Share on X](https://twitter.com/intent/tweet?text=Just%20read%20this%20on%20CEDclinic.com%3A%20Research%20Shows%20a%20Popular%20Anti-Aging%20Supplement%20May%20Lower%20Blood%20Pressure%20%40drcaplan&url=https%3A//www.verywellhealth.com/can-nmn-lower-blood-pressure-11938102)[in Share on LinkedIn](https://www.linkedin.com/sharing/share-offsite/?url=https%3A//www.verywellhealth.com/can-nmn-lower-blood-pressure-11938102)[🦥 Share on BlueSky](https://bsky.app/intent/compose?text=Just%20read%20this%3A%20Research%20Shows%20a%20Popular%20Anti-Aging%20Supplement%20May%20Lower%20Blood%20Pressure%20--%20via%20%40drcaplan.bsky.social%20https%3A//www.verywellhealth.com/can-nmn-lower-blood-pressure-11938102)[📷 Follow on Instagram](https://www.instagram.com/drbenjamincaplan/)[📝 Read more on Substack](https://substack.com/@doctorapproved)[🔔 Subscribe via RSS](https://cedclinic.com/category/cannabis-news/feed/) 📰 Source: [https://www.verywellhealth.com/can-nmn-lower-blood-pressure-11938102](https://www.verywellhealth.com/can-nmn-lower-blood-pressure-11938102) Table of Contents - [FAQ](#FAQ)[What is the clinical relevance rating of this cannabis news?](#What_is_the_clinical_relevance_rating_of_this_cannabis_news) - [What medical areas does this cannabis research relate to?](#What_medical_areas_does_this_cannabis_research_relate_to) - [Why is this cannabis news considered clinically significant?](#Why_is_this_cannabis_news_considered_clinically_significant) - [What should healthcare providers know about cannabis and cardiovascular effects?](#What_should_healthcare_providers_know_about_cannabis_and_cardiovascular_effects) - [How does this information affect patient safety considerations?](#How_does_this_information_affect_patient_safety_considerations) - [Related](#Related) ## FAQ #### What is the clinical relevance rating of this cannabis news? This article has been assigned CED Clinical Relevance #70, indicating “Notable Clinical Interest.” This rating suggests the findings represent emerging developments or policy changes that healthcare providers should monitor closely. #### What medical areas does this cannabis research relate to? The research focuses on cardiovascular health and blood pressure management. It also examines potential drug interactions and supplement considerations related to [cannabis use](https://cedclinic.com/cannabis-cardiovascular-health-insights-2024/). #### Why is this cannabis news considered clinically significant? The article presents emerging findings that could impact [patient care](https://cedclinic.com/cannabis-cardiovascular-risk-impact/) decisions. Healthcare providers need to stay informed about these developments to provide appropriate guidance to patients using cannabis therapeutically. #### What should healthcare providers know about cannabis and cardiovascular effects? [Cannabis use](https://cedclinic.com/cannabis-cardiovascular-health-insights-2024/) may have implications for blood pressure regulation and cardiovascular function. Providers should be aware of potential interactions with cardiovascular medications and supplements when treating patients who use cannabis. #### How does this information affect patient safety considerations? Understanding cannabis-related drug interactions and cardiovascular effects is crucial for patient safety. Healthcare providers should assess these factors when prescribing medications or recommending treatments for patients who use cannabis products. [https://cedclinic.com/contact/](https://cedclinic.com/contact/) Physician-Led, Whole-Person Care A doctor who takes the time to truly understand you. Personal care that starts with listening and is guided by experience and ingenuity. Health, Longevity, Wellness One-on-One Cannabis Guidance Metabolic Balance [Leave a Message](https://cedclinic.com/contact/) [Metabolic Care](https://cedclinic.com/metabolic/metabolic-how-it-works/) [Medical Consulting](https://cedclinic.com/book/) [Cannabis Care](https://cedclinic.com/book/) [https://cedclinic.com/contact/](https://cedclinic.com/contact/) RELATED READING AT CED CLINIC Continue exploring the evidence [Does marijuana cause lung cancer? Doctors reveal what the research says](https://cedclinic.com/cannabis-lung-cancer-research/) Explore current research on marijuana's impact on lung cancer risk, providing insights from medical professionals. [Read More](https://cedclinic.com/cannabis-lung-cancer-research/) [CBD vs THC Explained: Choosing the Right Option for UK Wellness](https://cedclinic.com/cannabinoid-selection-evidence-based-medicine-uk-wellness/) Understand the differences between CBD and THC to make informed wellness choices tailored to your needs. [Learn More](https://cedclinic.com/cannabinoid-selection-evidence-based-medicine-uk-wellness/) [Study reveals lung-brain link between smoking and neurodegeneration – News-Medical.Net](https://cedclinic.com/lung-brain-axis-cannabis-smoking-neurodegeneration/) New research uncovers connections between smoking-related lung damage and neurodegenerative diseases. [Discover Insights](https://cedclinic.com/lung-brain-axis-cannabis-smoking-neurodegeneration/) ### Related --- ### Verification & Medical Governance - **Lead Clinical Author:** Benjamin Caplan, MD - **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House). - **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`). - **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/). - **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637). - **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).