# Cannabis Dosing Needs More Than Guesswork

> **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637)
> **Publisher:** CED Clinic (https://cedclinic.com)
> **Canonical URL:** https://cedclinic.com/cannabis-dosing-needs-more-than-guesswork/
> **Published:** 2026-10-07T12:53:31-04:00 | **Last Modified / Clinically Audited:** 2026-10-07T12:53:31-04:00
> **Clinical Summary:** Cannabis has a highly individual dose-response curve, and effects can shift with product type, timing, metabolism, and other medications. Clinical guidance he

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Dr. Caplan’s Clinical Pearl
 

Cannabis has a highly individual dose-response curve, and effects can shift with product type, timing, metabolism, and other medications. Clinical guidance helps patients start low, adjust slowly, and recognize when side effects or tolerance are signaling that the plan needs attention.

 

 
 
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### Verification & Medical Governance

- **Lead Clinical Author:** Benjamin Caplan, MD
- **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House).
- **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`).
- **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/).
- **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637).
- **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).