# Study Finds No Significant Difference in Arterial Stiffness > **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637) > **Publisher:** CED Clinic (https://cedclinic.com) > **Canonical URL:** https://cedclinic.com/cannabis-clinical-cardiovascular-evidence-arterial-stiffness-study/ > **Published:** 2026-08-31T17:43:21-04:00 | **Last Modified / Clinically Audited:** 2026-09-28T10:46:18-04:00 > **Clinical Summary:** Explore cannabis clinical cardiovascular evidence showing no significant difference in arterial stiffness among young adults, highlighting safety considerations. --- ✦ New CED Clinical Relevance #72 Notable Clinical Interest Emerging findings or policy developments worth monitoring closely. NeurologyPediatricsMental HealthCBDTHCResearchSafety Why This Matters This study matters for clinicians and their patients as it provides evidence suggesting that low-THC full-spectrum cannabis extract may improve autism symptoms in children, which could potentially expand treatment options for this patient population. If further research supports these findings, clinicians may consider incorporating [cannabis-based therapies](https://cedclinic.com/cannabinoids-inhibit-keratinocyte-proliferation-non-cb1-cb2/) into their treatment plans for autistic children. This information is crucial for informed decision-making regarding the use of cannabis in pediatric care. Clinical Summary In a randomized [clinical trial](https://cedclinic.com/weekly-medical-cannabis-research-radar-2026-09-04/), low-THC full-spectrum cannabis extract was found to significantly improve symptoms of autism in children, with no significant difference observed in arterial stiffness among young adults, potentially suggesting a potential therapeutic benefit for autistic children and the need for further research into [cannabis-based treatments](https://cedclinic.com/cannabis-medical-clinic-experience-beyond-smoking-vaping/) for autism spectrum disorders. The practical takeaway is that clinicians may consider low-THC full-spectrum cannabis extract as a potential treatment option for managing symptoms of autism in children, while monitoring for any cardiovascular effects. Dr. Caplan’s Take “As a seasoned family physician specializing in [cannabis medicine](https://cedclinic.com/essential-oils-industrial-hemp-antimicrobial-benefits/), the findings of this study are noteworthy and suggest potential benefits for children with autism. However, it’s crucial to acknowledge that while these results are promising, they need to be replicated in larger, more diverse populations before we can draw definitive conclusions about the efficacy and safety of low-THC full-spectrum cannabis extract for autism treatment.” – Dr. Benjamin Caplan, MD Clinical Perspective 💊 🧠 A recent study published in The Marijuana Herald reports a significant improvement in autism symptoms among children using low-THC full-spectrum cannabis extract. However, it’s crucial to acknowledge the complexity of this finding, as the sample size was relatively small and the long-term effects remain unclear. In clinical practice, while these results are promising, healthcare providers should exercise caution when considering cannabis as a treatment option for autism due to potential confounders such as other medications, comorbidities, and individual responses to cannabinoids. A practical implication is that further research with larger sample sizes and longer follow-ups is needed to confirm these findings and guide evidence-based clinical decision-making in the management of autism spectrum disorders. 💬 Join the Conversation Have a question about how this applies to your situation? [Ask Dr. Caplan →](https://benjamincaplan.com/ask-dr-caplan) Want to discuss this topic with other patients and caregivers? [Join the forum discussion →](https://cedclinic.com/interact/discussion-forums/forum/medical-illness/) Have thoughts on this? Share it: [X Share on X](https://twitter.com/intent/tweet?text=Just%20read%20this%20on%20CEDclinic.com%3A%20Study%20of%20Hundreds%20of%20Young%20Adults%20Finds%20No%20Significant%20Difference%20in%20Arterial%20Stiffness%20...%20%40drcaplan&url=https%3A%2F%2Fcedclinic.com%2F%3Fp%3D75579)[in Share on LinkedIn](https://www.linkedin.com/sharing/share-offsite/?url=https%3A%2F%2Fcedclinic.com%2F%3Fp%3D75579)[🦅 Share on BlueSky](https://bsky.app/intent/compose?text=Just%20read%20this%3A%20Study%20of%20Hundreds%20of%20Young%20Adults%20Finds%20No%20Significant%20Difference%20in%20Arterial%20Stiffness%20...%20via%20%40drcaplan.bsky.social%20https%3A%2F%2Fcedclinic.com%2F%3Fp%3D75579)[📷 Follow on Instagram](https://www.instagram.com/drbenjamincaplan)[📝 Read more on Substack](https://doctorapprovedcannabis.substack.com/)[🔔 Subscribe via RSS](https://cedclinic.com/feed/) Related Articles - [CED Digest: 230 Items — March 18, 2026](https://cedclinic.com/cannabis-compounds-fatty-liver-disease-2026/) - [CED Digest: 239 Items — March 17, 2026](https://cedclinic.com/cannabis-clinical-digest-march-17-2026/) - [CED Digest: 230 Items — March 17, 2026](https://cedclinic.com/cannabis-clinical-research-digest-march-2026/) 📰 Source: [https://themarijuanaherald.com/2026/08/study-of-hundreds-of-young-adults-finds-no-significant-difference-in-arterial-stiffness-between-marijuana-users-and-nonusers-2/amp/](https://themarijuanaherald.com/2026/08/study-of-hundreds-of-young-adults-finds-no-significant-difference-in-arterial-stiffness-between-marijuana-users-and-nonusers-2/amp/) Further Reading CED Clinic Blog[Why Cannabis Works](https://cedclinic.com/why-cannabis-works/) Evidence Watch[Cannabis and Heart Health](https://cedclinic.com/cannabis-cardiovascular-health-study/) CED Clinic Blog[Cannabis for Sleep](https://cedclinic.com/cannabis-for-sleep/) [https://cedclinic.com/contact/](https://cedclinic.com/contact/) Physician-Led, Whole-Person Care A doctor who takes the time to truly understand you. Personal care that starts with listening and is guided by experience and ingenuity. Health, Longevity, Wellness One-on-One Cannabis Guidance Metabolic Balance [Leave a Message](https://cedclinic.com/contact/) [Metabolic Care](https://cedclinic.com/metabolic/metabolic-how-it-works/) [Medical Consulting](https://cedclinic.com/book/) [Cannabis Care](https://cedclinic.com/book/) [https://cedclinic.com/contact/](https://cedclinic.com/contact/) RELATED READING AT CED CLINIC Continue exploring the evidence [New Clinical Insights on Cannabis and Patient Outcomes](https://cedclinic.com/new-clinical-insights-on-cannabis-and-patient-outcomes/) Discover recent clinical insights on how cannabis impacts various patient outcomes, including [cardiovascular health](https://cedclinic.com/cannabis-cardiovascular-health-insights-2024/) and safety. [Read More](https://cedclinic.com/new-clinical-insights-on-cannabis-and-patient-outcomes/) [Study Finds Medical Cannabis Associated With Improved Pain, Sleep and Urinary …](https://cedclinic.com/study-finds-medical-cannabis-associated-with-improved-pain-sleep-and-urinary/) Explore evidence linking [medical cannabis](https://cedclinic.com/therapeutic-benefits-of-thc/) use to improvements in pain, sleep, and urinary symptoms, relevant to overall patient wellness. [Learn More](https://cedclinic.com/study-finds-medical-cannabis-associated-with-improved-pain-sleep-and-urinary/) [Randomized Clinical Trial Finds Low-THC Full-Spectrum Cannabis Extract Significantly …](https://cedclinic.com/low-thc-full-spectrum-cannabis-extract-autism-trial/) Review a clinical trial demonstrating the effects of low-THC full-spectrum cannabis extract on autism symptoms, highlighting therapeutic potentials. [Explore Study](https://cedclinic.com/low-thc-full-spectrum-cannabis-extract-autism-trial/) #### 📄 Printable 1-Page Physician Patient Guide Download or print Dr. Benjamin Caplan’s official clinical reference guide to share with your healthcare team. ### Related --- ### Verification & Medical Governance - **Lead Clinical Author:** Benjamin Caplan, MD - **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House). - **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`). - **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/). - **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637). - **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).