# The Use of Cannabidiol Suppositories for Sexual Pain > **Author:** Benjamin Caplan, MD (ABFM Board Certified, MA Lic. #240562, NPI: 1962722637) > **Publisher:** CED Clinic (https://cedclinic.com) > **Canonical URL:** https://cedclinic.com/cannabidiol-suppositories-sexual-pain-treatment-clinical-trial/ > **Published:** 2026-05-08T15:07:10-04:00 | **Last Modified / Clinically Audited:** 2026-09-28T17:15:37-04:00 > **Clinical Summary:** Clinical trial investigates cannabidiol suppositories sexual pain treatment research, evaluating CBD's potential for reducing intimate discomfort and improving --- CED Clinical Relevance  #68Notable Clinical Interest  Emerging findings or policy developments worth monitoring closely. 🧪 Clinical Trial Watch  |  CED Clinic Trial ID NCT07271030 Status Recruiting Condition Well-Being, Psychological Intervention Cannabidiol suppository intervention 1 Why This Matters Sexual pain disorders affect up to 20% of women and significantly impact [quality of life](https://cedclinic.com/cannabis-policy-enforcement-february-26-2026/), yet treatment options remain limited. This trial addresses a critical gap by investigating topical cannabidiol delivery for vulvodynia and dyspareunia, conditions where systemic medications often provide inadequate relief. Clinical Summary This randomized controlled trial is evaluating dose-specific cannabidiol suppositories for sexual [pain reduction](https://cedclinic.com/glp-1-receptor-agonists-pain-management/) over one month with 12-week follow-up. The study employs both quantitative pain measures and qualitative patient feedback to assess impact on sexual function, well-being, and [quality of life](https://cedclinic.com/cannabis-policy-enforcement-february-26-2026/). Currently recruiting participants, this appears to be an early-phase investigation with plans for larger-scale replication if results prove promising. Dr. Caplan’s Take “If positive, this trial could establish cannabidiol suppositories as a targeted, non-systemic option for sexual pain disorders where current treatments often fall short. The localized delivery approach may offer [therapeutic benefits](https://cedclinic.com/therapeutic-benefits-of-thc/) while minimizing systemic cannabinoid exposure.” Clinical Perspective 🧠 Patients experiencing sexual pain should discuss participation with their gynecologist or sexual medicine specialist, as this represents novel research in an underserved area. Clinicians should note the study’s focus on localized cannabinoid delivery, which may inform future treatment protocols for vulvovaginal pain conditions. 💬 Join the Conversation Have a question about how this applies to your situation? [Ask Dr. Caplan →](https://benjamincaplan.com/ask-dr-caplan) Want to discuss this topic with other patients and caregivers? [Join the forum discussion →](https://cedclinic.com/interact/discussion-forums/) Have thoughts on this? Share it: [𝕏 Share on X](https://twitter.com/intent/tweet?text=Just%20read%20this%20on%20CEDclinic.com%3A%20The%20Use%20of%20Cannabidiol%20Suppositories%20for%20Sexual%20Pain%20%40drcaplan&url=https%3A//clinicaltrials.gov/study/NCT07271030)[in Share on LinkedIn](https://www.linkedin.com/sharing/share-offsite/?url=https%3A//clinicaltrials.gov/study/NCT07271030)[🦥 Share on BlueSky](https://bsky.app/intent/compose?text=Just%20read%20this%3A%20The%20Use%20of%20Cannabidiol%20Suppositories%20for%20Sexual%20Pain%20--%20via%20%40drcaplan.bsky.social%20https%3A//clinicaltrials.gov/study/NCT07271030)[📷 Follow on Instagram](https://www.instagram.com/drbenjamincaplan/)[📝 Read more on Substack](https://substack.com/@doctorapproved)[🔔 Subscribe via RSS](https://cedclinic.com/category/cannabis-news/feed/) 📰 Source: [https://clinicaltrials.gov/study/NCT07271030](https://clinicaltrials.gov/study/NCT07271030) Table of Contents - [FAQ](#FAQ)[What is the cannabidiol suppository trial for sexual pain testing?](#What_is_the_cannabidiol_suppository_trial_for_sexual_pain_testing) - [How will researchers measure whether CBD suppositories help sexual pain?](#How_will_researchers_measure_whether_CBD_suppositories_help_sexual_pain) - [Is the CBD suppository trial still enrolling, and are results available?](#Is_the_CBD_suppository_trial_still_enrolling_and_are_results_available) - [Related](#Related) ## FAQ ### What is the cannabidiol suppository trial for sexual pain testing? It is a randomized controlled trial, registered as NCT07271030, evaluating dose-specific cannabidiol suppositories for reducing sexual pain. The intervention period is one month, and the study includes a 12-week follow-up period. ### How will researchers measure whether CBD suppositories help sexual pain? The trial uses both quantitative pain measures and qualitative feedback from patients. Together, these are meant to assess how the suppositories affect sexual function, well-being, and quality of life, in addition to pain. ### Is the CBD suppository trial still enrolling, and are results available? The trial is currently recruiting participants, so results have not yet been reported. It appears to be an early-phase investigation, and larger-scale replication is planned if the results prove promising. [https://cedclinic.com/contact/](https://cedclinic.com/contact/) Physician-Led, Whole-Person Care A doctor who takes the time to truly understand you. 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Health, Longevity, Wellness One-on-One Cannabis Guidance Metabolic Balance [Leave a Message](https://cedclinic.com/contact/) [Metabolic Care](https://cedclinic.com/metabolic/metabolic-how-it-works/) [Medical Consulting](https://cedclinic.com/book/) [Cannabis Care](https://cedclinic.com/book/) [https://cedclinic.com/contact/](https://cedclinic.com/contact/) ### Related --- ### Verification & Medical Governance - **Lead Clinical Author:** Benjamin Caplan, MD - **Credentials:** Board Certified in Family Medicine (ABFM), Founder & CMO CED Clinic & CED Foundation, Author of *The Doctor-Approved Cannabis Handbook* (Penguin Random House). - **Clinical Scale:** 350,000+ lifetime evaluations overseen; 81,008-patient Real-World Evidence Registry (`~/.ced_rwe_vault.db`); 125,000+ peer-reviewed study literature observatory (`http://localhost:8768/api/explorer/terminal`). - **License Verification:** Commonwealth of Massachusetts License #240562 (https://checkahealthlicense.mass.gov/). - **NPI Registry:** 1962722637 (https://npiregistry.cms.hhs.gov/provider-view/1962722637). - **Ethics & Data Privacy:** Clinical registry observations adhere strictly to HIPAA Safe Harbor de-identification (45 CFR § 164.514(b)) and criteria for secondary research exemption under 45 CFR § 46.104(d)(4).